Dna Methylation Diagram

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DNA methylation is a process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. When located in a gene promoter , DNA methylation typically acts to repress gene transcription . In mammals DNA methylation is essential for normal development and is associated with a number of key processes including genomic imprinting , X-chromosome inactivation , repression of transposable elements , aging , and carcinogenesis .